Despite being available for over 45 years, long acting injectable (LAI) antipsychotics remain an underutilized treatment option for people with serious and persistent mental illness. They are used primarily for individuals who struggle with adherence to antipsychotic medication and have been demonstrated through research to help:

  • Improve medication adherence
  • Reduce the occurrence and frequency of symptom relapse
  • Reduce hospitalizations
  • Improve treatment outcomes for this population

This Toolkit has resources that will assist you in obtaining information and resources pertaining to long acting injectables (LAIs). The purpose of the toolkit is to support your efforts to provide a seamless transition for your patients from the inpatient setting to the community.

Although all LAI antipsychotics medications are covered on the statewide preferred drug list, there are circumstances where prior authorization will be necessary. Provided below is the clinical guideline for prior authorization of antipsychotics.

PA DHS Prior Authorization of Antipsychotics – Pharmacy Services